becoming malnourished have been defined on the basis of poor intake in the recent past (6,9) and poor intake in combination with illness (10). Three systematic reviews that have included analyses of the effects of oral nutritional interventions in cancer patients have failed to demonstrate any clinical benefit of oral nutritional intervention (11,12) or benefits to QOL (13), but the conclusions were limited. None of the reviews included an analysis of weight, the analysis of QOL was limited to global QOL only, and some key studies were not included in the analysis. More recent trials have provided additional data in this area, and therefore, it is timely to reexamine this question. In addition, guidelines on nutritional support often do not capture the potential benefits of simple oral nutritional interventions and rely on data from studies of enteral and parenteral feeding (8).
The aim of this systematic review was
becoming malnourished have been defined on the basis of poor intake in the recent past (6,9) and poor intake in combination with illness (10). Three systematic reviews that have included analyses of the effects of oral nutritional interventions in cancer patients have failed to demonstrate any clinical benefit of oral nutritional intervention (11,12) or benefits to QOL (13), but the conclusions were limited. None of the reviews included an analysis of weight, the analysis of QOL was limited to global QOL only, and some key studies were not included in the analysis. More recent trials have provided additional data in this area, and therefore, it is timely to reexamine this question. In addition, guidelines on nutritional support often do not capture the potential benefits of simple oral nutritional interventions and rely on data from studies of enteral and parenteral feeding (8).The aim of this systematic review was
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