High fibrinolytic activity at the onset of AFE has been noticed by a few authors. In 1977, Graeff et al. [18] monitored a few parameters of fibrinolysis, starting from minute 15 of an embolic event. At that time, nearly the whole plasma fibrinogen pool underwent thrombin-plasmin transformations; fibrinogen concentration was only 15 mg %, and the levels of early and late products of fibrinogen degradation were estimated to be very high. The authors were convinced that AFE caused rapid DIC at first and reactive hyperfibrinolysis as the secondary process. Nowadays, the activity of the coagulation-fibrinolysis processes is assessed based on the level of D-di- mers.