However, there are few data on the effect of this intervention on a population basis and data are still lacking on the routine effectiveness of these new regimens especially in our local settings. So, it is hard to extrapolate directly from what has been reported in different countries due to difference in population and multiple socio economic factors that may affect the ultimate outcome obtained from these interventions. Moreover, a number of risk factors have been implicated with increasing risks of HIV transmission
10,23,25-31
, but the most important contributing factors haven’t been studied in our institution.
The current study was aimed at determining the effectiveness of different ARV regimens and identifying factors that may compromise the positive outcome of these regimens in Jimma University Specialized Hospital (JUSH). We hypothesized that there is no difference in the risk of mother-to-child transmission of HIV whether combination of three ARV or short course dual regimens and single dose nevirapine alone is used.