Patients who in the last 6 months experienced myocardial
infarction, unstable angina, stroke, transient
ischemic attack, decompensated heart failure requiring
hospitalization, or Class III/IV heart failure.
History or presence of Mobitz Type II second-degree
or third-degree atrioventricular block or sick sinus
syndrome, unless patient has a functioning pacemaker.
Baseline QTc interval of Q500 milliseconds.
Treatment with Class IA or Class III anti-arrhythmic
drugs.