Introduction
Fish aquaculture constitutes a rapidly growing industry worldwide.This has led to a concomitant increase in aquaculture intensity methods, which increase the susceptibility to disease outbreaks and the necessity use of the medicated diet (Jerbi et al., 2011). But the most dangerous is that, a large proportion of the world’s antimicrobial industrial production is used as prophylactics and as growth promoters that far outweigh their use as therapeutics (Bush et al., 2011; Cabello et al., 2013).
Especially, antibiotics are still used until now as growth promoters in some of the fish farms in Egypt.