Pooled data fr om two studies (Chiu 2008; Maasland 2007) indi-cated that e ducational and behavioural inter ventions for patientswere not associated with changes in mean LDL levels, althougha substantial level of statistical heter ogeneity was observed in thisanalysis (I2= 61%) (Analysis 1.6). One of the two studies includedin the analysis was individually associated with improvements inLDL levels (MD -0.39 mmol/L; 95% CI -0.73 to -0.05). How-ever, data were only presented for a subgroup of study participantswith hyperchole ste r ol aemia (i.e. those with the greatest potentialfor improvement) (Chiu 2008). Maasland 2007 reported signif-icant reductions in LDL during the course of the study for boththe intervention and control groups, with no significant differ-ences between the groups. OnlyChiu 2008 presented data on theachievement of LDL targets (LDL < 2.6 mmol/L or, if LDL notavailable, TC < 4.1 mmol/L) and no significant improvementswere reported (Chiu 2008)