When extracellular calcium level increases,
PTH and 1,25 dihydroxyvitamin D decrease, which leads to
a decrease in intracellular calcium in adipocytes, stimulating
lipolysis and lipogenesis inhibition.15–17,28 Nevertheless,
it is not known if calcium ions have the potential to penetrate
human skin and, if they cross it, does this cause an increase in
extracellular calcium; this aspect needs further investigation.
Magnesium plays an important role once it is picked up by
adipocytes to perform lipolysis, and as fatty acids are mobilized,
its concentration decreases, especially during aerobic
exercise; this is the reason why the application of body wrap
can favor the lipolysis process.14