The aim of this work is to analyze the efficiency and assess the risk (rating) of the listed in Athens Stock Exchange commercial banks for the period 2006-2012. The analysis includes two periods of comparison of banking organizations. The first period covers the years 2006-2009 and is characterized by increasing profitability and credit expansion both in Greece and abroad. The second period examines the years 2009-2012 and captures the impact on the banks of the economic crisis in Greece which erupted in the year 2009