Cancer accounts for 23% of all deaths in the United
States. It is the second leading cause of death after
heart disease, and the leading cause of death in those
younger than age 65 years. Colorectal cancer is the third
most common type of cancer in both men and women and
is the second and third leading cause of cancer-related
deaths in men and women, respectively. In 2006, an estimated
148 610 new cases of colorectal cancer occurred and
51 170 patients died of this disease (1, 2).
It is widely accepted that colorectal adenomatous polyps
are the precursors of the vast majority of colorectal
cancer cases, so the early detection and removal of these
lesions are presumed to reduce the incidence and mortality
of colorectal cancer. In addition, cases of cancer detected
by screening may be in the early stage and therefore curable.
Colorectal cancer has many characteristics of a disorder
that would be amenable to screening, as recently reviewed
by the U.S. Preventive Services Task Force
(USPSTF) (3). Several screening methods are available, but
despite the evidence of effectiveness, widespread routine
screening of eligible individuals by any method continues
to be low in the United States (4–7).
Cancer accounts for 23% of all deaths in the UnitedStates. It is the second leading cause of death afterheart disease, and the leading cause of death in thoseyounger than age 65 years. Colorectal cancer is the thirdmost common type of cancer in both men and women andis the second and third leading cause of cancer-relateddeaths in men and women, respectively. In 2006, an estimated148 610 new cases of colorectal cancer occurred and51 170 patients died of this disease (1, 2).It is widely accepted that colorectal adenomatous polypsare the precursors of the vast majority of colorectalcancer cases, so the early detection and removal of theselesions are presumed to reduce the incidence and mortalityof colorectal cancer. In addition, cases of cancer detectedby screening may be in the early stage and therefore curable.Colorectal cancer has many characteristics of a disorderthat would be amenable to screening, as recently reviewedby the U.S. Preventive Services Task Force(USPSTF) (3). Several screening methods are available, butdespite the evidence of effectiveness, widespread routinescreening of eligible individuals by any method continuesto be low in the United States (4–7).
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