Paper-based electrodes can be easily produced in various configurations (Figure 1) due to theinherent properties of this material, including thickness, flexibility and hydrophilicity. Consequently,paper-based platforms can be tailored to any desired application. In the context of electrochemicalbiosensors, paper materials have been used as a support substrate for all the electrodes composingthe electrochemical cell (working, reference and counter) [24,31,35], but also in combination withconventional electrodes