Helminthiasis is one of the most important group of parasitic diseases in Indo-Pakistan subcontinent resulting in heavy production losses in livestock. A wide variety of anthelmintics is used for the treatment of helminths in animals. However, the development of resistance in helminths against commonly used anthelmintics have always been a challenge faced by the animal health care professionals. Therefore, exploitation of anthelmintic potential of plants indigenous to Indo-Pak subcontinent is an area of research interest. This paper reviews the use of some indigenous plants as anthelmintics in animals.