By carefully designing the PD amplification circuit, the new
pyrosequencer is sensitive to 50 fmol of ssDNA template in a 50
lL pyrosequencing reaction. Due to the small size of PD as well
as the compact capillary-based dNTP dispenser, the dimensions
of a prototype of 8-channel pyrosequencer were 140W 158H
250D (mm), which is ideal for portable device.