Until more data are available, it would be prudent
to apply the recommendations of the antidepressant
boxed warning to all individuals being treated
pharmacologically for depressive illness, irrespective
of treatment modality (i.e., conventional or
alternative).
Despite the lack of rigorous regulatory oversight
of the manufacture, testing, and marketing of
dietary supplements, the use of alternative
products should not be categorically discouraged.
Some products, including SJW, represent potentially
legitimate treatment options.
It is important
that clinicians and other healthcare practitioners
recommend natural/herbal antidepressant products,
including SJW and SAM-e, judiciously and
with a sound understanding of the data that exists
to support such a recommendation.
Until more data are available, it would be prudentto apply the recommendations of the antidepressantboxed warning to all individuals being treatedpharmacologically for depressive illness, irrespectiveof treatment modality (i.e., conventional oralternative).Despite the lack of rigorous regulatory oversightof the manufacture, testing, and marketing ofdietary supplements, the use of alternativeproducts should not be categorically discouraged.Some products, including SJW, represent potentiallylegitimate treatment options.It is importantthat clinicians and other healthcare practitionersrecommend natural/herbal antidepressant products,including SJW and SAM-e, judiciously andwith a sound understanding of the data that existsto support such a recommendation.
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