Methods
Setting and participants
A cross-sectional study was performed among 1091 endometrial
cancer survivors registered within the Eindhoven cancer registry
(ECR) of the Comprehensive Cancer Center South (CCCS). The ECR records data on all patients newly diagnosed with cancer in the southern
part of the Netherlands, an area with 10 hospitals serving 2.3 million
inhabitants. The ECR was used to select patients diagnosed with endometrial cancer between January 1st 1999 and October 1st 2007 in 10
hospitals. All individuals (age 18–84 years) diagnosed with endometrial cancer FIGO stages I–II (classification 1988) were eligible for participation. Deceased patients were excluded by linking the ECR with
the Central Bureau of Genealogy. In addition, patients who had less
than 1 year follow-up were excluded. Patients with an additional malignancy or recurrent disease were also excluded, as this may have
influenced their follow-up (Fig. 1). Ethical approval for the study
was obtained from a Medical Ethics Committee.