Although the rate of HIV infection is very low in Iran (about 0.2%), it has an upward trend.[5] Based on recent statistics, 23,902 PLWH were identified in Iran, but the real rate is estimated to be more than 100,000 people. Men and women with HIV/AIDS comprise 91% and 9%, respectively, and needle sharing among drug users has been reported as the most frequent cause of AIDS in Iran.