All spectra of proteins were submitted to database
searching using online MASCOT program (http://www.matrixscience.com), against NCBInr databases. The searching parameters were as follow: 0.15Da mass
tolerance for peptides and 0.25Da mass tolerance of TOF–TOF fragments,one allowed trypsin miscleavage,
carbamidomethyl of Cys as fixedmodification, and
oxidation of Met, pyro-Glu formation of N-terminal
Gln and Glu as variable modification.