Long-term intake of diet comprising reheated vegetable oil leads
to endothelial dysfunction. Repeatedly heated dietary vegetable oil
promotes oxidative stress, resulting in NO inactivation and reduced
bioavailability. Moreover, antioxidant effect of fresh vegetable oil
against free radicals may be reduced gradually as the oil is repeatedly
heated. Production of free radicals and reduction of antioxidant and
vitamin levels eventually lead to oxidative stress. Oxidative stress
and endothelial dysfunction play pivotal roles in the pathogenesis of
cardiovascular diseases, which may be controlled by diet modification.
Ingestion of repeatedly heated vegetable oil should be restricted due
to the detrimental consequences on health