Even nowadays some spices and culinary herbs play an important role in primary health care and in the treatment of diabetes, especially in developing countries [2]. Recently, they have been recognized as sources of various phytochemicals, many of which possess a high antioxidant activity, which, however, can be affected by various factors such as variety, and growing and storage conditions. In particular, almost all spices and the majority of culinary herbs are rich in polyphenols, plant secondary metabolites having high antioxidant activity [3–5] arising from their ability to scavenge a wide spectrum of free radicals, chelate redox-active metals, and/or quench singlet oxygen [4]. They are also known to play an important role in stabilizing lipid peroxidation and in inhibiting various types of oxidizing enzymes [6]. In addition, most of these phenolic compounds have antimicrobial properties that together with their antioxidant capacity are a valuable aid in food preservation. Spices and culinary herbs also possess a high anti-glycant potential arising mainly from their polyphenol content [7]. The non-enzymatic glycation of proteins (Maillard reaction) is a process closely linked to oxidative stress and is associated with increased production of hydrogen peroxide and other highly reactive oxidants that in turn leads to the formation of complex compounds, the advanced glycation end-products (AGEs), which alter the structure and functions of proteins. AGEs are involved in the pathogenesis of diabetes, and contribute to several pathophysiologies associated with aging and diabetes mellitus, such as chronic renal insufficiency, Alzheimer's disease, nephropathy, neuropathy, and cataract [7]. Hyperglycemia accelerates the formation of AGEs and the degree of accumulation of AGEs is correlated to the severity of diabetic complications [7].