Fig. 2.
Proposed orthologs to lamina proteins in Saccharomyces cerevisiae, Caenorhabditis elegans, Drosophila melanogaster and vertebrates. The first number shows the number of genes; the number of splicing isoforms is in parentheses. Brown indicates that no ortholog was found; light yellow indicates the presence of a single gene; yellow indicates multiple genes or multiple isoforms. Question marks indicate genes not yet found in the still-incomplete vertebrate databases. Data was obtained from the GenBank database. The S. cerevisiae protein Sad1 contains a region of homology to UNC-84, but is positioned on the outer nuclear membrane and ER, and was excluded from this figure 15.