Time magazine featured Dr. Bruton and his medical discovery in the May 18, 1953 issue.[3][6] There is also a milder form of X-linked congenital Swiss-type agammaglobunemia referred to as Bruton-Gitlin syndrome. It is characterized by decreased amounts of humoral gammaglobulin in serum, with cellular functional deficiencies as well. There is also a defect in the Btk gene in this condition.