Objective: To develop a new antibacterial antibiotic from streptomyces strains were isolated from a sample of marine soil in and around Tamil Nadu coastal areas.
Methods: Totally 35 strptomyces species were isolated from marine soil by spread plate method and were screened for their antagonistic activity against five different pathogenic bacterial strains by cross streak method and agar well diffusion method. One of the strain was found to be more active against five different bacterial strains.
Results: The strain was identified as Streptomyces coelicolor Strain SU6 (JQ828940) by 16S rRNA partial gene sequencing. The antibacterial compound produced by the active strain was identified by GC-MS report as 3-ethyl,3-methyl heptane and Diisodecyl ether.
Conclusion: The observations from this study confirmed that Streptomyces isolated from marine environment may be potentially used for extracting novel antibiotics for treating bacterial infections in human.