This photograph is shown the cell palette after incubation with sample. This is control, and arbutin, kojic acid, Applephenon, and procyanidin fraction in Applephenon. You can see that the cells with Applephenon are inhibited melanin production and become more white than control.
This is the cell photograph and black spot is melanin. You do not find melanin in the cells cultured with Applephenon.