midate
Etomidate is formulated in 35% propylene glycol (osmolality = 4640 mOsm/L), which
may cause pain, phlebitis, thrombosis and hemolysis when administered into a small vein or as a
continuous infusion; it should be administered with fluids. Etomidate is associated with rapid
induction and recovery and variable cardiopulmonary effects. It is noncummulative with
repeated dosages. It decreases cerebral blood flow, intracranial pressure, and intra-ocular
pressure. It is expensive compared to other anesthetics and may interfere with adrenal cortical
function for several hours.21 It has no analgesic properties. It remains relatively expensive.