21. Free radical and antioxidant properties of Alpinia galanga (L.) willd
By Das, Archana; Santhy, Kumaran Sivanandan
From International Journal of Pharma and Bio Sciences (2015), 6(4), 378-385. Language: English, Database: CAPLUS
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Copyright © 2016 American Chemical Society (ACS). All Rights Reserved.
Copyright © 2016 American Chemical Society (ACS). All Rights Reserved.
Copyright © 2016 American Chemical Society (ACS). All Rights Reserved.
Copyright © 2016 American Chemical Society (ACS). All Rights Reserved.
Natural antioxidants presented in food and other biol. materials have attracted considerable interest in the last few
decades. In the present study, the antioxidant activity of Methanol Ext. of Alpinia galanga (MEAG) was detd. by using
three complementary in vitro assays: Inhibition of DPPH and H2O2 radical & reducing power assay. The enzymic and
non enzymic antioxidants were detd. in the methanol ext. of the rhizome by suitable colorimetric procedures. The results
indicated a strong antioxidant potential of the plant ext. The effective concn. (EC50) sufficient to elicit 50% of a max.
effect was calcd. to be 64 and 66 mg/mL for the DPPH and H2O2 radical scavenging resp. The multiple antioxidant
activity of MEAG was evident as it showed significant reducing power. The activity of Catalase in the rhizome was found
to be max. when compared to other enzymes assessed. The level of non-enzymic antioxidants (Ascorbic acid, a-
tocopherol and polyphenols) were found in considerable amts. From the results, it could be inferred that Alpinia galanga
possesses innate antioxidant properties and therefore can be utilized for supplementing the antioxidant needs in the diet
and for the treatment of various disorders caused due to oxidative damage.