reverse phase is easier to use than normal phase.
reverse phase has a hydrophobic stationary phase which can be applied to a wide range of molecules, it works well in retention time for most of the organic analytes.(70-80% of common analytes can be meansured by RP-HPLC)
reverse phase has more options for the chromatographer. It also allows precise control of variables as organic solvent type and concentration, and pH
normal-phase can be use for compounds that are too hydrophobic or hydrophilic for using reversed-phase
compounds that are not soluble in water or that may decompose in water are candidates for normal-phase chromatography.
one of the main uses of normal-phase chromatography is for the separetion of isomers.
now can you give the answer to the questions below?
what is the difference between normal phase HPLC and reverse phase HPLC
which form is more commonly used; normal phase or reverse phase
dose a hydrophobic (non-polar) analyte has affinty to a polar stationary phase