Effect of AEBO on histamine-induced peritoneal vascular permeability
As shown in Figure 3, both doses of AEBO (50 and 150 mg/kg) notably inhibited the histamine-induced increase
of dye leakage into the peritoneal cavity, with an inhibitory rate up to 99%. The potency of AEBO was similar to that of loratadine (91.1% inhibition).