LDL-receptor-related protein (LRP) [68] transfers cho- lesterol from chylomicron remnants that carry exogen- ous cholesterol from the intestine. Recently, also in the intestine transporters have been identified that are able to transfer cholesterol, the ABC transporter ABCA1 that is defective in Tangier disease [69] and the Niemann- Pick C1-like protein 1 (NPC1L1) [70]. The role of the