This was observed in the study of Margosh et al. (2005), where in HPP treatments between 0.1 and
800 MPa for 30 min at 20 oC, staphylococcal SE suffered no change in
their immuno-reactivity. It was also observed in the study of Rene'- Trouillefou et al. (2010), in which SEA solutions were submitted to 600 MPa/15 min at 20 oC, that there was no significant immuno-
reactivity difference between non-pressurized and pressurized SEA. Furthermore, in the study of Rene'-Trouillefou et al. (2010), it was observed that under 600 MPa/15 min at 20 oC spectral changes (fully reversible under decompression) occurred in SEA.