However, these findings of increased glycine concentration indicate a possible role played by glycine in the pathogenesis of HD and also suggest that glycine binding site of NMDA receptor could be an attractive target for HD drug development.
Taurine deficiency is associated with anxiety, epilepsy, hyperac- tivity and depression [32] and taurine supplementation can relieve these symptoms
treatment with taurine increased striatal GABA concentration and reduced oxidative stress and hyperactive movement
Taurine's role as an inducer of inhibitory neurotransmitter, an antioxidant, and neuro- protection makes it a potential therapeutic agent for HD.