Treatment of ABGE increased concentration of serum IL-2 in tumor-bearing mice. To determine whether treatment of ABGE has an immunomodulative action, concentrations of serum IL-2 in MFC-bearing mice were assessed. As shown in Fig. 3C, ELISA analysis indicated that, compared with the negative control, the activity of IL-2 increased slightly with the low‑dosage ABGE treatment (p>0.05). In contrast, significant increase of IL-2 was observed in the medium- and high-dosage groups compared with negative control group (p