In the first set, at-risk laboratory workers in Sweden were immunized with LVS NDBR101 Lot 11.
The set was comprised of five sets of paired pre- and post-vaccination samples and an additional three post-vaccination serum samples.
NDBR lot 11 was prepared as per the vial instructions. Briefly, the vaccine preparation was reconstituted in 2.0 mL of water to give a concentration of 2.5 × 109 CFU/mL.
A droplet of approximately 20 μL (containing ∼5 × 107 CFU) was administered by scarification using a bifurcated needle to puncture the skin.