This study indicated that inhuman way of animal han-dling, incidence of non-ambulation and death of animals were common due to poor loading and unloading proce- dures, overcrowding and falling on the truck, hunger, disease, and unfavorable weather the animals were ex- posed to during transport and inside Kumasi cattle mar- ket. Only during the transport from source to Kumasi, more than 16% of expected revenue was lost due to in- appropriate animal handling. The poor hygienic condi- tions of the slaughtering procedures and meat distribution to the butcheries using unhygienic vehicles disclosed the existing problems concerning the safety and quality of meat. These issues of animal welfare and meat safety and quality should get attention and further studies should be carried out and improvements must be planned by the concerning bodies.