Results
Serum progesterone levels were significantly increased
in stressed rats (control-S, 35.6 ± 4.8 ng/mL and
OVX-S, 21.9 ± 4.0 ng/mL) compared to control (10 ± 2.9
ng/mL) and OVX (2.8 ± 0.5 ng/mL) groups. Factive was higher
in the OVX groups (OVX, 25.9 ± 3.4 kN/m2 and OVX-S,
26.3 ± 3.0 kN/m2) than in control groups (control, 16.4 ± 1.2
kN/m2 and control-S, 14.4 ± 0.9 kN/m2). Regarding the
potential molecular mechanisms, Factive correlated with
MyBP-C phosphorylation, while myofilament Ca2+-sensitivity
inversely correlated with serum progesterone levels
when the mean values were plotted for all animal groups.
Fpassive was unaffected by any treatment.