There are at least 14 federal regulations and 3 agencies, including the Environmental Protection Agency (EPA), Food and Drug Administration (FDA), and the Occupational Safety and Health Administration (OSHA), that are involved in the regulation of occupational skin exposure in the United States.28 Historically, efforts to control workplace exposures to hazardous agents have focused on inhalation rather than skin exposures. As a result, assessment strategies and methods are well developed for evaluating inhalation exposures in the workplace; however, standardized methods are currently lacking for measuring and assessing skin exposures.29 There are currently no occupational exposure limits (OELs) set for dermal exposures; however, chemicals with risk associated with dermal penetration are given a skin notation assignment (S) as a guidance to warn against potential for increased risk of systemic toxicity because of dermal penetration in additional to inhalation exposure. NIOSH has 142 skin notations assigned to chemicals, OSHA lists 159 notations in the PocketGuide, and over 219 chemicals have a skin notation assigned by the American Conference of Industrial Hygienists (ACGIH).