ICU admission was mainly
indicated for sickle-cell disease–related events, especially acute
chest syndrome. Mechanical ventilation, vasoactive drugs, and
renal replacement therapy were administered to 25 (18%), 10
(7%), and 10 (7%) episodes, respectively. The complicated outcome
group (n = 28; 20%) was characterized by a more aggressive
acute disease within the 48 hours preceding ICU admission,
with a higher respiratory rate, a more frequent acute kidney injury,
and a more sustained drop of hemoglobin (all p < 0.01). All
nine deaths (7%) were sickle-cell disease related.
ICU admission was mainlyindicated for sickle-cell disease–related events, especially acutechest syndrome. Mechanical ventilation, vasoactive drugs, andrenal replacement therapy were administered to 25 (18%), 10(7%), and 10 (7%) episodes, respectively. The complicated outcomegroup (n = 28; 20%) was characterized by a more aggressiveacute disease within the 48 hours preceding ICU admission,with a higher respiratory rate, a more frequent acute kidney injury,and a more sustained drop of hemoglobin (all p < 0.01). Allnine deaths (7%) were sickle-cell disease related.
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