Abstract—This experiment was performed with the purpose ofinvestigating effect of additional blend of probiotics Saccharomycescerevisiae and Lactobacillus acidophilus on plasma fatty acid profilesparticularly conjugated linoleic acid (CLA) in growing goats fed cornsilage, and selected the optimal levels of the probiotics for further study.Twenty-four growing crossbred (Thai native x Anglo-Nubian) goats thatweighed (14.2 ± 2.3) kg, aged about 6 months, were purchased andallocated to 4 treatments according to Randomized Complete BlockDesign (RCBD) with 6 goats in each treatment. The blocks were made byweight into heavy, medium, and light goats and each of the treatmentscontained two goats from each of the blocks. In the mean time, ruminalaverage pH unaffected, but the NH3-N and also plasma urea nitrogen(p<0.05), total volatile fatty acid (p>0.05) were raised, but propionicproportion (p<0.05) and butyric proportion (p>0.05) were reduced inconcurrent with raise of acetic proportion and resultantly C2:C3 ratio(p>0.05). On plasma fatty acid profiles, total saturated fatty acids(p>0.05) was increased, and contrasted with decrease of C15:0(p<0.01), C16:0 (p>0.05), and C18-C22 polyunsaturated fatty acids(p<0.05 or p<0.01). In addition, the experiment proved that thesupplemented probiotics was in force for heightening CLA (p<0.01);for raising desirable fatty acids (p<0.05); for reducing ratio of PUFA:SFA (p > 0.05) และเพิ่มอัตราส่วนของ n6:n3 (p < 0.05)
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