The body weight and food intake were not altered in
the study animals that were treated with grape seed extract.
Table 1 shows the levels of LPO in control and grape seed
extract-treated young and aged rats. The spinal cord, cerebral
cortex, striatum and the hippocampus regions of aged rats
showed a highly significant (P < 0.001) increase in the LPO.
The levels of LPO were significantly decreased (P < 0.001)
on grape seed extract administration