Slide Coagulase Test: Detects clumping factor (formerly referred as cell-bound coagulase)
Clumping factor directly coverts fibrinogen to fibrin causing agglutination
Heavy suspension of organism is made on glass slide and mixed with drop of plasma
Agglutination indicates a positive test:
Indicates Staphylococcus aureus
Some species of Coagulase negative staphylococcus can be positive
Negative results should be confirmed