Adducts formed by the interaction of acetaldehyde with erythrocyte membranes have been detected in the erythrocytes of alcohol abusers. These adducts may be associated with ethanol-induced macrocytosis, a condition characterized by unusually large numbers of enlarged erythrocytes in the blood (Niemela and Parkkila 2004). Macrocytosis is a marker for alcohol abuse.
Finally, acetaldehyde can form adducts by interacting with compounds known as biogenic amines,3 which include, among others, neurotransmitters such as serotonin and dopamine. These adducts may have pharmacological effects on the nervous system. (For more information on adduct formation and other detrimental effects of acetaldehyde, see the article by Quertemont and Didone, p. 258).
ROS Formation. As mentio
Adducts formed by the interaction of acetaldehyde with erythrocyte membranes have been detected in the erythrocytes of alcohol abusers. These adducts may be associated with ethanol-induced macrocytosis, a condition characterized by unusually large numbers of enlarged erythrocytes in the blood (Niemela and Parkkila 2004). Macrocytosis is a marker for alcohol abuse.Finally, acetaldehyde can form adducts by interacting with compounds known as biogenic amines,3 which include, among others, neurotransmitters such as serotonin and dopamine. These adducts may have pharmacological effects on the nervous system. (For more information on adduct formation and other detrimental effects of acetaldehyde, see the article by Quertemont and Didone, p. 258).ROS Formation. As mentio
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