Little controlled data are available regarding the treatment
of bipolar disorder complicated by OCD. OCD generally
require long-term treatment with antiobsessional agents
include SSRIs. However, adequate mood stabilization should
be achieved before antidepresants are used to treat residual
anxiety symptoms in order to minimize antidepressantinduced
mania or cycling (10). Another study emphasized
that drug treatment with clomipramine and to a lesser
extent, with SSRIs was associated with hypomanic switches
in OCD-bipolar patients, especially in those, who were not
concomitantly treated with mood stabilizers