In this paper, a sensitive electrochemical method for the detection
of AIV H5N1 gene sequences using a DNA aptamer immobilized
hybrid nanomaterial-modified electrode was developed, as shown
in Fig. 1. The hybrid nanomaterial (MWNT/PPNWs/GNPs) provides
a porous structure with a large effective surface area, highly electrocatalytic
activities and electronic conductivity. In order to enhance
the recognition and selectivity of the biosensor, DNA aptamers were
used as capture probes. The results indicate that this strategy may
provide a sensitive, selective, simple, and inexpensive detection
method for the AIV genotype.
In this paper, a sensitive electrochemical method for the detectionof AIV H5N1 gene sequences using a DNA aptamer immobilizedhybrid nanomaterial-modified electrode was developed, as shownin Fig. 1. The hybrid nanomaterial (MWNT/PPNWs/GNPs) providesa porous structure with a large effective surface area, highly electrocatalyticactivities and electronic conductivity. In order to enhancethe recognition and selectivity of the biosensor, DNA aptamers wereused as capture probes. The results indicate that this strategy mayprovide a sensitive, selective, simple, and inexpensive detectionmethod for the AIV genotype.
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