The question arises whether aloe vera is safe. Studies in mice
revealed no acute toxicity in therapeutic doses.32 In high doses,
however, a decrease of CNS activity was noticed. During chronic
treatment, there was a decrease in red cell count and significant
sperm damage.32 No systematic investigations exist in humans.
In the reviewed trials, no withdrawals or serious adverse reactions were reported. Three patients experienced allergic reactions.15
This corresponds with anecdotal reports relating to contact
dermatitis and hypersensitivity.33-38 One recent publication
details the suspension of a physician by the United States
Virginia Board of Medicine because of causing the death of ‘several’
of his patients through injections of aloe vera for cancer.39
One text on herbal treatments1 warns of oral use during pregnancy
but lists no further adverse effects or contraindications.