The patient was admitted to the hospital and intravenous fluid therapy was promptly initiated to correct the infant’s tachycardia, polypnea, and low blood pH, by attempting volume repletion with 2 subsequent doses of 0.9% sodium chloride at 20 mL/kg over 60 minutes. A solution containing dextrose 5% plus electrolytes was administered soon after the second dose of normal saline to attain the slow correction of hypernatremia. Diuresis was reestablished within four hours of rehydration therapy. Digestive losses of water and electrolytes were offset by oral rehydration solution (ORS), at an initial dose of 10 mL/kg and thereafter replaced volume per volume depending on the amount of stool losses. Enterol (yeast of Saccharomyces boulardii) was initiated as an adju- vant treatment to ORS. Metabolic acidosis was difficult to correct during the first 48 hours because of large liquid losses due to diarrhea. Despite the difficulties experienced to restore the electrolytic balance, the baby showed an outstanding digestive tolerance throughout the entire hospital stay, which allowed continuation of enteral nutrition with lactose-free formula milk (Novalac Diarinova).