The clinical aspects of this study, including a comprehensive
description and discussion of the FMT-treated patient population
and individual case metadata, are provided in a separate
publication (Dutta et al., submitted). Fecal samples were collected
from 14 patient-donor pairs and used for this study (Fig. 1; Table
1). All patients had at least three recurrences of C. difficile infection
and were treated with at least three courses of antibiotics. Fecal
samples were collected before and after FMT from patients and, at
corresponding time points, from their respective donors, which
included family members (spouses and children) and friends (Fig.
1).