In the present study, the fabrication of a new modified electrode for electrocatalytic
oxidation of noradrenalin, based on the delphinidin immobilized on silver nanoparticles
modified glassy carbon electrode. Cyclic voltammetry was used to investigate the redox
properties of this modified electrode. The surface charge transfer rate constant (ks) and the
charge transfer coefficient (a) for the electron transfer between the glassy carbon electrode
and the immobilized delphinidin were calculated. The differential pulse voltammetry
exhibited two linear dynamic ranges and a detection limit of 0.40mM for noradrenalin
determination. Moreover, the present electrode could separate the oxidation peak potentials
of ascorbic acid, noradrenalin, uric acid, and tryptophan in a mixture. The usefulness
of this nanosensor was also investigated for the determination of ascorbic acid,
noradrenalin, and uric acid in pharmaceutical and biological fluid samples with satisfactory
results.