Leonel et al. (2010), who used a similar methodology to determine
EE in the spray chilling production of solid lipid microparticles loaded
with glucose in solution, reported that the amount of effectively encapsulated
active material ranged from 78.3 to 97.8%. According to these
authors, the greater the concentration of glucose in the solution, the
lower the EE. Moreover, unlike what we observed for microparticles
loaded with AA, Chambi, Alvim, Barrea-Arellano, and Grosso (2008) reported
that the size of the particle did not influence the encapsulation
efficiency. Therefore the real amount of encapsulated substance is strictly
related to the equipment used for the microencapsulation.