In the present work, an environmentally friendly CTS-based nanocomposite coating was designed/developed. In the coating formulations, CTS was used as the main antimicrobial component and modified starch served as the binders instead of petroleum-based latex binders. More importantly, TiO2nanoparticles, one of the most potential ultraviolet (UV) light-sensitive inorganic bactericide with intrinsic photoelectric properties (Geng, Filipe, & Pelton,2008), was employed as a functional nanofiller in this nanocomposite coatings. For a deep understanding of coating properties, the rheological behavior of the obtained CTS/TiO2nanocompos-ite coatings was investigated. Subsequently, surface application of CTS/TiO2 nanocomposite coatings to cellulosic paper was conducted, and the change in related properties of the products was identified. In general, the developed CTS/TiO2nanocomposite coatings were effective in imparting the cellulosic paper with