value at each gestational age) and outcomes of each
case are shown in Table 3. Eight cases (55%) of this
group had normal outcomes (normal karyotype and no
other gross anomaly at birth). It could be assumed that
these cases received unnecessary invasive prenatal
diagnosis for karyotype testing. The other five cases
with abnormal chromosome, including four cases of
trisomy and one case of 45 XO. Some of these cases
had abnormal NT and structural anomaly such as cystic
hygroma, radial ray defect or omphalocele. However,
one case of cystic hygroma was associated with
normal karyotype, one case had skeletal abnormality
with thickened NT and the other case had no data of
karyotype or other anomaly at birth because of spontaneous
abortion.