Conclusion s
Beside s the early clin ical diagno sis at the onset of symp -toms , our result s indicated that urin e samp le analysis
wa s a noninva sive diagnostic appr oach, and the time-frames for positive dete ction in urine were longe r than
that in serum [6]. Serum samp les can have a high de-te ction rate (>50% ) in the first week after the onset of in-fe ction. Howe ver, the la st positiv e dete ction of virus in
serum samp les wa s no later than disea se day 11. Ur ine
samp le dete ction rates can be >50% between disea se day
6 to 16 , with the la st positive dete ction of virus on day
16 [6]. In this ca se, our data were con sistent with pre-vious stud ies that repor ted a longer tim eframe of posi-tive dete ction ( Table 2). The full DEN V-2 genome wa s