Results
We identified 582 infants less than 32 weeks gestation that underwent ophthalmologic screening for ROP. Overall, 412 infants had no ROP and 170 had ROP (57 with Stage I, 65 with Stage II, and 48 with Stage III). There were no cases of Stage IV or V ROP in this study cohort. No infants in this trial received insulin therapy for hyperglycemia.
Univariate analyses
Table 1 outlines the results of the univariate analysis. Not surprisingly, infants diagnosed with ROP were of lower birthweight and gestational age compared to those without ROP, and were more likely to have been affected by a PDA, neonatal sepsis, and intraventricular hemorrhage. Infants with ROP were also more likely to have significant lung disease and to have received postnatal glucocorticoid therapy than those without ROP. There were no differences between ROP and non-ROP subjects with respect to rate of c-section delivery, gender, or NEC. Infants with ROP experienced a greater mean number of days with hyperglycemia (7 vs. 2, p = < 0.0001).
ResultsWe identified 582 infants less than 32 weeks gestation that underwent ophthalmologic screening for ROP. Overall, 412 infants had no ROP and 170 had ROP (57 with Stage I, 65 with Stage II, and 48 with Stage III). There were no cases of Stage IV or V ROP in this study cohort. No infants in this trial received insulin therapy for hyperglycemia.Univariate analysesTable 1 outlines the results of the univariate analysis. Not surprisingly, infants diagnosed with ROP were of lower birthweight and gestational age compared to those without ROP, and were more likely to have been affected by a PDA, neonatal sepsis, and intraventricular hemorrhage. Infants with ROP were also more likely to have significant lung disease and to have received postnatal glucocorticoid therapy than those without ROP. There were no differences between ROP and non-ROP subjects with respect to rate of c-section delivery, gender, or NEC. Infants with ROP experienced a greater mean number of days with hyperglycemia (7 vs. 2, p = < 0.0001).
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